Dysregulated apoptosis and NFκB expression in COPD subjects

• Published in: Respiratory research Vol. 10; no. 1; p. 24
• Main Authors: Brown, Vanessa, Elborn, J Stuart, Bradley, Judy, Ennis, Madeleine
• Format: Journal Article
• Language: English
• Published: BioMed Central Ltd 18.03.2009; BioMed Central; BMC

BACKGROUND: The abnormal regulation of neutrophil apoptosis may contribute to the ineffective resolution of inflammation in chronic lung diseases. Multiple signalling pathways are implicated in regulating granulocyte apoptosis, in particular, NFκB (nuclear factor-kappa B) signalling which delays con...