Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development - Zhou, Shu-Feng; Zhou, Zhi-Wei; Yang, Li-Ping; Cai, Jian-Ping (Current medicinal chemistry, 2009)
Keywords: Aryl Hydrocarbon Hydroxylases - antagonists & inhibitors; Aryl Hydrocarbon Hydroxylases - genetics; Aryl Hydrocarbon Hydroxylases - metabolism; Catalytic Domain; Chromosomes, Human, Pair 10; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System - genetics; Cytochrome P-450 Enzyme System - metabolism; Drug Discovery; Enzyme Inhibitors - chemistry; Enzyme Inhibitors - pharmacology; Humans; Receptors, Cytoplasmic and Nuclear - metabolism; Structure-Activity Relationship; Substrate Specificity