Expression of adrenomedullin in adipose tissue of lean and obese women

• Published in: European journal of endocrinology Vol. 155; no. 1; pp. 177 - 185
• Main Authors: Paulmyer-Lacroix, O, Desbriere, R, Poggi, M, Achard, V, Alessi, M-C, Boudouresque, F, Ouafik, L’H, Vuaroqueaux, V, Labuhn, M, Dutourand, A, Grino, M
• Format: Journal Article
• Language: English
• Published: England European Society of Endocrinology 01.07.2006; Oxford Univ. Press
• Subjects: Adipose Tissue - metabolism; Adrenomedullin; Adult; Anthropometry; Blood Chemical Analysis; Body Weight - physiology; Cancer; Cell Differentiation - physiology; Clinical Studies; Female; Hemodynamics - physiology; Humans; Immunohistochemistry; In Situ Hybridization; Life Sciences; Middle Aged; Obesity - metabolism; Peptides - genetics; Peptides - metabolism; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger - biosynthesis; Stem Cells - metabolism; Stromal Cells - metabolism; Tumor Necrosis Factor-alpha - biosynthesis

Objective: Adrenomedullin (AM), a potent vasodilatator and antioxidative peptide, was shown recently to be expressed by adipose tissue. The aim of our study was to investigate the precise localization of AM within human adipose tissue, and to examine AM regulation in obesity. Design: Subcutaneous (S...