Loss of Mrap2 is associated with Sim1 deficiency and increased circulating cholesterol - Novoselova, T V; Larder, R; Rimmington, D; Lelliott, C; Wynn, E H; Gorrigan, R J; Tate, P H; Guasti, L; O’Rahilly, S; Clark, A J L; Logan, D W; Coll, A P; et al. (Journal of endocrinology, 2016)
Keywords: Adaptor Proteins, Signal Transducing; Animals; Anxiety - genetics; Anxiety - metabolism; Basic Helix-Loop-Helix Transcription Factors - genetics; Basic Helix-Loop-Helix Transcription Factors - metabolism; Behavior, Animal - physiology; Body Weight - genetics; Cholesterol - blood; Corticotropin-Releasing Hormone - genetics; Corticotropin-Releasing Hormone - metabolism; Eating - genetics; Energy Metabolism - genetics; Lipid Metabolism - genetics; Mice; Mice, Knockout; Motor Activity - genetics; Neurons - metabolism; Oxytocin - genetics; Oxytocin - metabolism; Paraventricular Hypothalamic Nucleus - metabolism; Receptor Activity-Modifying Proteins - genetics; Receptor Activity-Modifying Proteins - metabolism; Repressor Proteins - genetics; Repressor Proteins - metabolism; Thyrotropin-Releasing Hormone - genetics; Thyrotropin-Releasing Hormone - metabolism; MC4R; CRH; metabolism; OXT; AVP; TRH; SIM1; MRAP2; obesity; melanocortin; accessory protein