Hepatic effects of duloxetine-I: non-clinical and clinical trial data - Wernicke, Joachim; Pangallo, Beth; Wang, Fujun; Murray, Isabelle; Henck, Judith W; Knadler, Mary Pat; D'Souza, Deborah N; Uetrecht, Jack P (Current drug safety, 2008)
Keywords: Adrenergic Uptake Inhibitors - adverse effects; Adrenergic Uptake Inhibitors - toxicity; Alanine Transaminase - blood; Alkaline Phosphatase - blood; Animals; Aspartate Aminotransferases - blood; Bilirubin - blood; Biomarkers - blood; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Consumer Product Safety; Drug Evaluation, Preclinical; Duloxetine Hydrochloride; Humans; Liver - drug effects; Liver - enzymology; Liver Diseases - enzymology; Risk Assessment; Risk Factors; Serotonin Uptake Inhibitors - adverse effects; Serotonin Uptake Inhibitors - toxicity; Species Specificity; Thiophenes - adverse effects; Thiophenes - toxicity