Demographic and clinical characteristics associated with variations in antibody response to BNT162b2 COVID-19 vaccination among healthcare workers at an academic medical centre: a longitudinal cohort analysis

• Published in: BMJ open Vol. 12; no. 5; p. e059994
• Main Authors: Ebinger, Joseph E, Joung, Sandy, Liu, Yunxian, Wu, Min, Weber, Brittany, Claggett, Brian, Botting, Patrick G, Sun, Nancy, Driver, Matthew, Kao, Yu Hung, Khuu, Briana, Wynter, Timothy, Nguyen, Trevor-Trung, Alotaibi, Mona, Prostko, John C, Frias, Edwin C, Stewart, James L, Goodridge, Helen S, Chen, Peter, Jordan, Stanley C, Jain, Mohit, Sharma, Sonia, Fert-Bober, Justyna, Van Eyk, Jennifer E, Minissian, Margo B, Arditi, Moshe, Melmed, Gil Y, Braun, Jonathan G, McGovern, Dermot P B, Cheng, Susan, Sobhani, Kimia
• Format: Journal Article
• Language: English
• Published: England British Medical Journal Publishing Group 24.05.2022; BMJ Publishing Group LTD; BMJ Publishing Group
• Series: Original research
• Subjects: Academic Medical Centers; Adult; Age; Antibodies; Antibodies, Viral; Antibody Formation; BNT162 Vaccine; Cohort analysis; Cohort Studies; Comorbidity; Coronaviruses; COVID-19; COVID-19 - epidemiology; COVID-19 - prevention & control; COVID-19 Vaccines; Demography; Drug dosages; Ethnicity; Female; Health Personnel; Humans; Hypertension; Immunoglobulin G; Infections; Infectious Diseases; Longitudinal Studies; Male; Medical personnel; Middle Aged; Prospective Studies; Proteins; SARS-CoV-2; Serology; Severe acute respiratory syndrome coronavirus 2; Vaccination; Variables; Work environment; Workers; COVID-19; hypertension; infectious diseases

ObjectivesWe sought to understand the demographic and clinical factors associated with variations in longitudinal antibody response following completion of two-dose regiment of BNT162b2 vaccination.DesignThis study is a 10-month longitudinal cohort study of healthcare workers and serially measured a...