DSARna: RNA Secondary Structure Alignment Based on Digital Sequence Representation

• Published in: Combinatorial chemistry & high throughput screening Vol. 24; no. 7; p. 1042
• Main Authors: Gao, Longjian, Xu, Chengzhen, Song, Wangan, Xiao, Feng, Wu, Xiaomin, Shi, Li, Sun, Yuxuan, Li, Jun
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.01.2021
• Subjects: Algorithms; Computational Biology; Nucleic Acid Conformation; RNA - chemistry; Sequence Alignment; Sequence Analysis, RNA; Dynamic programming; structural alignment; RNA secondary structure; path matrix

With increasing applications and development of high-throughput sequencing, knowledge of the primary structure of RNA has expanded exponentially. Moreover, the function of RNA is determined by the secondary or higher RNA structure, and similar structures are related to similar functions, such as the...