LIMD2 is the Signature of Cell Aging-immune/Inflammation in Acute Myocardial Infarction

• Published in: Current medicinal chemistry Vol. 31; no. 17; p. 2400
• Main Authors: Tao, Ping, Chen, Xiaoming, Xu, Lei, Chen, Junteng, Nie, Qinqi, Xu, Mujuan, Feng, Jianyi
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.01.2024
• Subjects: Cellular Senescence; Humans; Inflammation - genetics; Inflammation - metabolism; LIM Domain Proteins - genetics; LIM Domain Proteins - metabolism; MicroRNAs - genetics; MicroRNAs - metabolism; Molecular Docking Simulation; Myocardial Infarction - genetics; Myocardial Infarction - immunology; Myocardial Infarction - metabolism; Myocardial Infarction - pathology; RNA, Messenger - genetics; RNA, Messenger - metabolism; immune; Acute myocardial infarction; ceRNAs; inflammation; cell aging; LIMD2

Acute myocardial infarction (AMI) is an age-dependent cardiovascular disease in which cell aging, immunity, and inflammatory factors alter the course; however, cell aging-immune/inflammation signatures in AMI have not been investigated. Based on the GEO database to obtain microRNA (miRNA) sequencing...