Effects of vitamin D binding protein phenotypes and vitamin D supplementation on serum total 25(OH)D and directly measured free 25(OH)D

• Published in: European journal of endocrinology Vol. 174; no. 4; pp. 445 - 452
• Main Authors: Sollid, Stina T, Hutchinson, Moira Y S, Berg, Vivian, Fuskevåg, Ole M, Figenschau, Yngve, Thorsby, Per M, Jorde, Rolf
• Format: Journal Article
• Language: English
• Published: England Bioscientifica Ltd 01.04.2016; BioScientifica
• Subjects: Aged; Clinical medical disciplines: 750; Clinical Study; Dietary Supplements; Endocrinology: 774; Endokrinologi: 774; Female; Genetic Association Studies; Humans; Klinisk medisinske fag: 750; Male; Medical disciplines: 700; Medisinske Fag: 700; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Prediabetic State - genetics; Prediabetic State - metabolism; Protein Binding - genetics; VDP; Vitamin D - administration & dosage; Vitamin D - analogs & derivatives; Vitamin D - analysis; Vitamin D - blood; Vitamin D - metabolism; Vitamin D Deficiency - genetics; Vitamin D Deficiency - metabolism; Vitamin D-Binding Protein - blood; Vitamin D-Binding Protein - genetics; Vitamin D-Binding Protein - metabolism

ObjectiveTo determine the relationship between serum total 25-hydroxyvitamin D (25(OH)D), directly measured free 25(OH)D and calculated free 25(OH)D with regard to vitamin D-binding protein (DBP) phenotypes, sex, BMI, age and season, and their interrelationship to vitamin D supplementation.Design, p...