The Role of Inflammasomes in Atherosclerosis and Stroke Pathogenesis

• Published in: Current pharmaceutical design Vol. 26; no. 34; p. 4234
• Main Authors: Sarmah, Deepaneeta, Datta, Aishika, Raut, Swapnil, Sarkar, Ankan, Shah, Birva, Bohra, Mariya, Singh, Upasna, Jagtap, Priya, Baidya, Falguni, Kalia, Kiran, Wang, Xin, Dave, Kunjan R, Yavagal, Dileep R, Bhattacharya, Pallab
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.01.2020
• Subjects: Atherosclerosis - drug therapy; Humans; Inflammasomes; Inflammation; Plaque, Atherosclerotic; Stroke - drug therapy; atherosclerosis; NLRP; therapies; Inflammasomes; inflammation; stroke

Inflammation is a devastating outcome of cerebrovascular diseases (CVD), namely stroke and atherosclerosis. Numerous studies over the decade have shown that inflammasomes play a role in mediating inflammatory reactions post cellular injury occurring after a stroke or a rupture of an atherosclerotic...