Irreversible multitargeted ErbB family inhibitors for therapy of lung and breast cancer - Subramaniam, Deepa; He, Aiwu Ruth; Hwang, Jimmy; Deeken, John; Pishvaian, Michael; Hartley, Marion L; Marshall, John L (Current cancer drug targets, 2015)
Keywords: Animals; Antineoplastic Agents - adverse effects; Antineoplastic Agents - therapeutic use; Breast Neoplasms - drug therapy; Breast Neoplasms - enzymology; Breast Neoplasms - metabolism; Drugs, Investigational - adverse effects; Drugs, Investigational - therapeutic use; ErbB Receptors - antagonists & inhibitors; ErbB Receptors - metabolism; Female; Humans; Lung Neoplasms - drug therapy; Lung Neoplasms - enzymology; Lung Neoplasms - metabolism; Male; Molecular Targeted Therapy; Neoplasm Proteins - antagonists & inhibitors; Neoplasm Proteins - metabolism; Protein Kinase Inhibitors - adverse effects; Protein Kinase Inhibitors - therapeutic use; Receptor, Epidermal Growth Factor - antagonists & inhibitors; Receptor, Epidermal Growth Factor - metabolism; Receptor, ErbB-2 - antagonists & inhibitors; Receptor, ErbB-2 - metabolism; Receptor, ErbB-3 - antagonists & inhibitors; Receptor, ErbB-3 - metabolism; Receptor, ErbB-4 - antagonists & inhibitors; Receptor, ErbB-4 - metabolism