Effect of PUFAs Oral Administration on the Amount of Apoptotic Caspases Enzymes in Gastric Cancer Patients Undergoing Chemotherapy

• Published in: Anti-cancer agents in medicinal chemistry Vol. 17; no. 1; p. 93
• Main Authors: Dolatkhah, Homayun, Movahedian, Ahmad, Somi, Mohammad-Hossein, Aghaei, Mahmud, Samadi, Naser, Mirza-Aghazade, Ahmad, Esfahani, Ali
• Format: Journal Article
• Language: English
• Published: Netherlands 2017
• Subjects: Adenocarcinoma - drug therapy; Adenocarcinoma - genetics; Adenocarcinoma - pathology; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents - administration & dosage; Antineoplastic Agents - therapeutic use; Apoptosis - drug effects; Caspase 3 - genetics; Caspase 8 - genetics; Caspase 9 - genetics; Caspases - analysis; Caspases - genetics; DNA Damage - drug effects; Fatty Acids, Omega-3 - administration & dosage; Fatty Acids, Omega-3 - therapeutic use; Fatty Acids, Omega-6 - administration & dosage; Fatty Acids, Omega-6 - therapeutic use; Fatty Acids, Unsaturated - administration & dosage; Fatty Acids, Unsaturated - therapeutic use; Female; Humans; Male; Middle Aged; Stomach - drug effects; Stomach - metabolism; Stomach - pathology; Stomach Neoplasms - drug therapy; Stomach Neoplasms - genetics; Stomach Neoplasms - pathology; Up-Regulation - drug effects

Gastric cancer is the fourth most common cancer and the second cause of death in the world. According to the studies, the gastric cancer is relatively sensitive to chemotherapy. The aim of this study was to investigate the association of oral administer PUFAs with Caspase enzymes in patients with ga...