The potential for antimicrobials to adversely affect mental state

This is a case report highlighting the influence that antimicrobials (clarithromycin in particular) can have on one's mental state. We discuss the case of a middle-aged woman who presented to an acute admissions unit under Irish Mental Health Act for involuntary admission because of concerns ex...

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Published inBMJ case reports Vol. 2013; p. bcr2013009659
Main Authors Lally, Leona, Mannion, Laura
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group LTD 05.07.2013
BMJ Publishing Group
SeriesCase Report
Subjects
Anti-Infective Agents - adverse effects
Antibiotics
Back pain
Bipolar Disorder - chemically induced
Bipolar Disorder - diagnosis
Ciprofloxacin - analogs & derivatives
Clarithromycin - adverse effects
Commitment of Mentally Ill
Confusion - chemically induced
Emotional disorders
Europe (West)
Female
Humans
Infections
Mental health
Middle Aged
Organotechnetium Compounds
Psychosis
Reminder of Important Clinical Lesson
Urine
White
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Abstract This is a case report highlighting the influence that antimicrobials (clarithromycin in particular) can have on one's mental state. We discuss the case of a middle-aged woman who presented to an acute admissions unit under Irish Mental Health Act for involuntary admission because of concerns expressed by her family and general practitioner regarding a recent change in behaviour and onset of irritable mood. This lady was diagnosed with an episode of mania that was thought to be precipitated by a combination of psychosocial stressors, recent discontinuation of psychotropic medication and complicated by a recent course of clarithromycin.
AbstractList This is a case report highlighting the influence that antimicrobials (clarithromycin in particular) can have on one's mental state. We discuss the case of a middle-aged woman who presented to an acute admissions unit under Irish Mental Health Act for involuntary admission because of concerns expressed by her family and general practitioner regarding a recent change in behaviour and onset of irritable mood. This lady was diagnosed with an episode of mania that was thought to be precipitated by a combination of psychosocial stressors, recent discontinuation of psychotropic medication and complicated by a recent course of clarithromycin.
Author Lally, Leona
Mannion, Laura
AuthorAffiliation Department of Psychiatry , Galway University Hospital , Galway , Ireland
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Cites_doi 10.1097/00004714-200202000-00012
10.1093/jac/32.4.627
10.1176/ajp.155.11.1626
10.1016/S0272-6386(96)90043-8
10.1093/clinids/20.6.1563
10.1093/clinids/22.3.595
10.1017/S1461145703003882
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  doi: 10.1017/S1461145703003882
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StartPage bcr2013009659
SubjectTerms Anti-Infective Agents - adverse effects
Antibiotics
Back pain
Bipolar Disorder - chemically induced
Bipolar Disorder - diagnosis
Ciprofloxacin - analogs & derivatives
Clarithromycin - adverse effects
Commitment of Mentally Ill
Confusion - chemically induced
Emotional disorders
Europe (West)
Female
Humans
Infections
Mental health
Middle Aged
Organotechnetium Compounds
Psychosis
Reminder of Important Clinical Lesson
Urine
White
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Title The potential for antimicrobials to adversely affect mental state
URI http://dx.doi.org/10.1136/bcr-2013-009659
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