Anti-β2GPI-domain I antibody is associated with extra-criteria manifestations in a large prospective antiphospholipid syndrome cohort in China

• Published in: Lupus science & medicine Vol. 10; no. 2; p. e000924
• Main Authors: Zhou, Yangzhong, Hu, Chaojun, Qi, Wanting, Long, Yin, Huang, Can, Wang, Qian, Tian, Xinping, Zhao, Jiuliang, Li, Mengtao, Zeng, Xiaofeng
• Format: Journal Article
• Language: English
• Published: London Lupus Foundation of America 01.08.2023; BMJ Publishing Group LTD; BMJ Publishing Group
• Series: Original research
• Subjects: Anemia; Antibodies; antiphospholipid antibodies; antiphospholipid syndrome; Autoimmune diseases; Biomarker Studies; Cardiovascular disease; Classification; Coronary vessels; Demographics; Hypertension; lupus erythematosus, systemic; Obstetrics; Thrombocytopenia; Thrombosis; Vein & artery diseases

BackgroundAnti-β2GPI-domain I (β2GPI-DI) antibody is pathogenic in patients with antiphospholipid syndrome (APS), but its additional clinical associations and diagnostic value are controversial.MethodsA total of 378 patients were included, of which 119 patients diagnosed with primary APS, 50 with AP...