Computed tomographic findings in a case of feline insulinoma
Insulinomas are functional insulin-secreting tumours of the beta cells of the pancreatic islets which are rare in cats. Clinical signs are a result of hypoglycaemia and include seizures, collapse, weakness, ataxia, disorientation, mental dullness and visual disturbances. An 11-year-old male neutered...
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Published in | Veterinary record case reports Vol. 8; no. 2 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
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British Veterinary Association
01.06.2020
Blackwell Publishing Ltd |
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Abstract | Insulinomas are functional insulin-secreting tumours of the beta cells of the pancreatic islets which are rare in cats. Clinical signs are a result of hypoglycaemia and include seizures, collapse, weakness, ataxia, disorientation, mental dullness and visual disturbances. An 11-year-old male neutered domestic shorthair cat was presented with a history of having a single abnormal neurological episode. Persistent hypoglycaemia, hyperinsulinaemia and the presence of a well-defined pancreatic nodule on abdominal ultrasound resulted in a suspected diagnosis of insulinoma. Multiphasic CT angiography revealed a well-defined, homogeneous pancreatic mass which was isoattenuating to pancreatic parenchyma on precontrast images, had marked contrast enhancement in the arterial phase and moderate enhancement in the venous phase. CT angiography was a useful imaging modality for evaluating this case of histologically confirmed malignant insulinoma and its associated metastases. |
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AbstractList | Insulinomas are functional insulin‐secreting tumours of the beta cells of the pancreatic islets which are rare in cats. Clinical signs are a result of hypoglycaemia and include seizures, collapse, weakness, ataxia, disorientation, mental dullness and visual disturbances. An 11‐year‐old male neutered domestic shorthair cat was presented with a history of having a single abnormal neurological episode. Persistent hypoglycaemia, hyperinsulinaemia and the presence of a well‐defined pancreatic nodule on abdominal ultrasound resulted in a suspected diagnosis of insulinoma. Multiphasic CT angiography revealed a well‐defined, homogeneous pancreatic mass which was isoattenuating to pancreatic parenchyma on precontrast images, had marked contrast enhancement in the arterial phase and moderate enhancement in the venous phase. CT angiography was a useful imaging modality for evaluating this case of histologically confirmed malignant insulinoma and its associated metastases. |
Author | Swallow, Adam Genain, Marie-Aude Shorten, Eimear McCallum, Katie Elizabeth Holzhausen, Cornelia Hughes, Katherine |
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Cites_doi | 10.1111/j.1748-5827.2007.00404.x 10.1111/j.1939-1676.1992.tb00336.x 10.1111/j.1748-5827.2002.tb00023.x 10.1259/bjr.71.841.9534694 10.2460/javma.2003.223.812 10.1111/j.1939-1676.2008.0267.x 10.1080/01652176.2018.1481545 10.1111/j.1740-8261.2007.00251.x 10.2214/ajr.181.4.1810987 10.1292/jvms.15-0077 10.1136/vr.137.3.65 10.1111/j.1740-8261.2008.00340.x 10.1892/0891-6640(2005)19<15:COUCTA>2.0.CO;2 10.1080/02841859709171257 10.1055/s-0038-1623719 10.1002/9781118785676.ch30 |
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Localization with dynamic spiral CT publication-title: Acta Radiol contributor: fullname: Chung MJ – ident: e_1_2_9_18_1 doi: 10.1080/01652176.2018.1481545 – ident: e_1_2_9_15_1 doi: 10.1259/bjr.71.841.9534694 – ident: e_1_2_9_20_1 doi: 10.1111/j.1748-5827.2002.tb00023.x – ident: e_1_2_9_16_1 doi: 10.2214/ajr.181.4.1810987 – ident: e_1_2_9_6_1 doi: 10.2460/javma.2003.223.812 – ident: e_1_2_9_8_1 doi: 10.1055/s-0038-1623719 – start-page: 1762 volume-title: Textbook of veterinary internal medicine year: 2017 ident: e_1_2_9_9_1 contributor: fullname: Schoeman JP – ident: e_1_2_9_10_1 doi: 10.1292/jvms.15-0077 – ident: e_1_2_9_3_1 doi: 10.1111/j.1939-1676.1992.tb00336.x – ident: e_1_2_9_17_1 doi: 10.1111/j.1740-8261.2007.00251.x – start-page: 315 volume-title: Veterinary computed tomography year: 2011 ident: e_1_2_9_19_1 doi: 10.1002/9781118785676.ch30 contributor: fullname: Cáceres AV – volume: 26 start-page: 453 year: 1990 ident: e_1_2_9_4_1 article-title: Pancreatic endocrine tumor in a cat: clinical, pathological, and immunohistochemical evaluation publication-title: J Am Anim Hosp Assoc contributor: fullname: O’Brien TD – ident: e_1_2_9_12_1 doi: 10.1136/vr.137.3.65 – volume: 21 start-page: 741 year: 1985 ident: e_1_2_9_5_1 article-title: Functional pancreatic islet cell tumor in a cat publication-title: J Am Anim Hosp Assoc contributor: fullname: McMillan FD – ident: e_1_2_9_7_1 doi: 10.1111/j.1939-1676.2008.0267.x – ident: e_1_2_9_13_1 doi: 10.1111/j.1740-8261.2008.00340.x – ident: e_1_2_9_2_1 doi: 10.1111/j.1748-5827.2007.00404.x |
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Snippet | Insulinomas are functional insulin-secreting tumours of the beta cells of the pancreatic islets which are rare in cats. Clinical signs are a result of... Insulinomas are functional insulin‐secreting tumours of the beta cells of the pancreatic islets which are rare in cats. Clinical signs are a result of... |
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SubjectTerms | Case reports Cats computed tomography (CT) diagnostic imaging Hypoglycemia Laboratories Lymphatic system Mesentery Metastasis Neuroendocrine tumors oncology Pancreas Surgeons Surgery Tumors Ultrasonic imaging |
Title | Computed tomographic findings in a case of feline insulinoma |
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