Phenotypical changes and clinical significance of CD4+/CD8+ T cells in SLE

• Published in: Lupus science & medicine Vol. 9; no. 1; p. e000660
• Main Authors: Yuan, Shiwen, Zeng, Yanting, Li, Jiawei, Wang, Cuicui, Li, Weinian, He, Zhixiang, Ye, Jinghua, Li, Fangfei, Chen, Yi, Lin, Xiaojun, Yu, Na, Cai, Xiaoyan
• Format: Journal Article
• Language: English
• Published: London Lupus Foundation of America 01.06.2022; BMJ Publishing Group LTD; BMJ Publishing Group
• Series: Original research
• Subjects: Biomarker Studies; Clinical significance; lupus erythematosus, systemic; lupus nephritis; Lymphocytes; T-lymphocytes, helper-inducer

ObjectiveT cells display significant phenotypical changes and play multiple roles in promoting the immune response in SLE. The frequencies of T cell subpopulations in SLE are still not well understood. To better understanding the phenotypic abnormalities of T cells in SLE will help us to clarify dis...