Neutrophil MiRNA-128-3p is Decreased During Active Phase of Granulomatosis with Polyangiitis

• Published in: Current genomics Vol. 16; no. 5; pp. 359 - 365
• Main Authors: Surmiak, Marcin, Hubalewska-Mazgaj, Magdalena, Wawrzycka-Adamczyk, Katarzyna, Musial, Jacek, Sanak, Marek
• Format: Journal Article
• Language: English
• Published: Bentham Science Publishers Ltd 01.07.2015

Granulomatosis with polyangiitis is a rare chronic inflammatory disease. In this multisystem autoimmune disorder neutrophils cause small vessels necrosis and infiltrate perivascular tissue to form granulomas. Progression of the disease is evaluated by the symptoms score and by a titer of antineutrop...