Jejunal villous atrophy and granulomatous inflammation responding to a gluten--free diet

• Published in: Gut Vol. 18; no. 10; pp. 814 - 816
• Main Authors: Bjorneklett, A, Fausa, O, Refsum, S B, Torsvid, H, Sigstad, H
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd and British Society of Gastroenterology 01.10.1977; BMJ Publishing Group LTD
• Subjects: Celiac Disease - complications; Celiac Disease - diet therapy; Female; Gastric Mucosa - pathology; Gastrointestinal Diseases - pathology; Glutens; Granuloma, Giant Cell - complications; Granuloma, Giant Cell - diet therapy; Humans; Jejunum - pathology; Liver - pathology; Liver Diseases - diet therapy; Middle Aged
• ISSN: 0017-5749; 1468-3288; 1458-3288
• DOI: 10.1136/gut.18.10.814

A 48 year old female patient with intestinal malabsorption and subtotal to total jejunal villous atrophy also had granulomatous inflammation characterised by numerous epitheloid and giant cell granulomas in the stomach, the jejunum, and the liver, On a gluten-free diet a complete remission was achieved that included disappearance of the granulomatous inflammation. It is suggested that the granulomas in this case were manifestations of the gluten intolerance.