Adiponectin oligomers as potential indicators of adipose tissue improvement in obese subjects

• Published in: European journal of endocrinology Vol. 169; no. 1; pp. 37 - 43
• Main Authors: De Rosa, Anna, Monaco, Maria Ludovica, Capasso, Mario, Forestieri, Pietro, Pilone, Vincenzo, Nardelli, Carmela, Buono, Pasqualina, Daniele, Aurora
• Format: Journal Article
• Language: English
• Published: Bristol BioScientifica 01.07.2013
• Subjects: Adiponectin - blood; Adiponectin - genetics; Adiponectin - metabolism; Adipose Tissue - metabolism; Adult; Bariatric Surgery; Biological and medical sciences; Biomarkers - blood; Blotting, Western; Body Mass Index; Case-Control Studies; Chromatography, Gel; Clinical Study; Endocrinopathies; Female; Fundamental and applied biological sciences. Psychology; Heparin, Low-Molecular-Weight - blood; Humans; Male; Medical sciences; Metabolic diseases; Middle Aged; Obesity; Obesity, Morbid - blood; Obesity, Morbid - metabolism; Obesity, Morbid - surgery; Real-Time Polymerase Chain Reaction; Receptors, Adiponectin - blood; RNA, Messenger - isolation & purification; Vertebrates: endocrinology; Weight Loss; Human; Obesity; Improvement; Adipose tissue; Nutrition disorder; Endocrinology; Nutritional status; Indicator; Adiponectin

ObjectiveAdiponectin is an adipocytokine that exerts beneficial effects on obesity and related disorders by two receptors (ADIPORs). Adiponectin is produced as a monomer that circulates in serum as different oligomers. The oligomerization state and the tissue expression of adiponectin and ADIPORs ar...