Serious infections in patients with VEXAS syndrome: data from the French VEXAS registry

• Published in: Annals of the rheumatic diseases Vol. 83; no. 3; pp. 372 - 381
• Main Authors: de Valence, Benjamin, Delaune, Marion, Nguyen, Yann, Jachiet, Vincent, Heiblig, Mael, Jean, Alexis, Riescher Tuczkiewicz, Stanislas, Henneton, Pierrick, Guilpain, Philippe, Schleinitz, Nicolas, Le Guenno, Guillaume, Lobbes, Hervé, Lacombe, Valentin, Ardois, Samuel, Lazaro, Estibaliz, Langlois, Vincent, Outh, Roderau, Vinit, Julien, Martellosio, Jean-Philippe, Decker, Paul, Moulinet, Thomas, Dieudonné, Yannick, Bigot, Adrien, Terriou, Louis, Vlakos, Alexandre, de Maleprade, Baptiste, Denis, Guillaume, Broner, Jonathan, Kostine, Marie, Humbert, Sebastien, Lifermann, Francois, Samson, Maxime, Pechuzal, Susann, Aouba, Achille, Kosmider, Olivier, Dion, Jeremie, Grosleron, Sylvie, Bourguiba, Rim, Terrier, Benjamin, Georgin-Lavialle, Sophie, Fain, Olivier, Mekinian, Arsène, Morgand, Marjolaine, Comont, Thibault, Hadjadj, Jerome, Melki, Isabelle, Fenaux, Pierre, Ades, Lionel, Audemard, Alexandra, Ebbo, Mikael, Jamilloux, Yvan, Rauzy, Odile Beyne, Belot, Alexandre, Borie, Raphaël, Mathian, Alexis, Arnaud, Laurent, Chasset, François, Bouaziz, Jean-David, Sujobert, Pierre, Benhamou, Ygal, Sauvetre, Gaetan, El-Karoui, Khalil, Rodrigues, François
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd and European League Against Rheumatism 01.03.2024; Elsevier Limited; BMJ Publishing Group
• Series: Annals of the Rheumatic Diseases
• Subjects: Age; Aged; Anemia; Arthralgia; Autoinflammatory disorders; Azacitidine; Bacteriophages; Cytokines; Disease prevention; Enzymes; Glucocorticoids; Hematology; Humans; Immune System Diseases; Immunodeficiency; Inflammation; Janus Kinase Inhibitors; Life Sciences; Medical prognosis; Monoclonal antibodies; Multivariate analysis; Mutation; Myelodysplastic Syndromes; Nosocomial infections; Patients; Retrospective Studies; Risk factors; Severe acute respiratory syndrome coronavirus 2; Skin Diseases, Genetic; Therapeutics; Tumor Necrosis Factor Inhibitors; Urinary tract; Vacuoles; France; Tumor Necrosis Factor Inhibitors; Immune System Diseases; Inflammation; Glucocorticoids; Therapeutics

IntroductionVacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome is an acquired autoinflammatory monogenic disease with a poor prognosis whose determinants are not well understood. We aimed to describe serious infectious complications and their potential risk factors.MethodsRetr...