Integrated analysis of mRNA and protein expression profiling in tubal endometriosis

• Published in: Reproduction (Cambridge, England) Vol. 159; no. 5; pp. 601 - 614
• Main Authors: Qi, Hang, Zhang, Huiyu, Zhao, Xiaoya, Qin, Ya, Liang, Guiling, He, Xiaoqing, Zhang, Jian
• Format: Journal Article
• Language: English
• Published: England Bioscientifica Ltd 01.05.2020
• Subjects: Adult; Chromatography, Liquid; Computational Biology; Cytokines - metabolism; Endometriosis - genetics; Endometriosis - metabolism; Fallopian Tube Diseases - genetics; Fallopian Tube Diseases - metabolism; Fallopian Tubes - metabolism; Female; Gene Expression Profiling; Humans; Middle Aged; Proteome; Proteomics; RNA, Messenger - metabolism; Tandem Mass Spectrometry; Transcriptome

Tubal endometriosis (tubal EM) is a subtype of endometriosis (EM) associated with fallopian tube impairments and infertility. Since the molecular mechanism underlying tubal EM is not clear, we assume that an aberrant transcriptome of fallopian tube epithelium and microenvironment changes caused by c...