Tuberculosis associated with Mycobacterium tuberculosis Beijing and non-Beijing genotypes: a clinical and immunological comparison

• Published in: BMC infectious diseases Vol. 6; no. 1; p. 105
• Main Authors: Sun, Yong-Jiang, Lim, T K, Ong, Adrian Kheng Yeow, Ho, Benjamin Choon Heng, Seah, Geok Teng, Paton, Nicholas I
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 05.07.2006; BioMed Central; BMC
• Subjects: Adult; Biomarkers - analysis; China; Cytokines - biosynthesis; Cytokines - blood; Cytokines - genetics; Cytokines - immunology; Enzyme-Linked Immunosorbent Assay; Female; Genotype; Humans; Lung - pathology; Male; Middle Aged; Mycobacterium tuberculosis; Mycobacterium tuberculosis - classification; Mycobacterium tuberculosis - genetics; Mycobacterium tuberculosis - immunology; Th2 Cells - immunology; Tuberculosis, Pulmonary - immunology; Tuberculosis, Pulmonary - microbiology; China

The Mycobacterium tuberculosis Beijing genotype is biologically different from other genotypes. We aimed to clinically and immunologically compare human tuberculosis caused by Beijing and non-Beijing strains. Pulmonary tuberculosis patients were prospectively enrolled and grouped by their M. tubercu...