Effect of mosquito salivary gland treatment on vesicular stomatitis New Jersey virus replication and interferon alpha/beta expression in vitro

• Published in: Journal of medical entomology Vol. 40; no. 2; p. 199
• Main Authors: Limesand, K H, Higgs, S, Pearson, L D, Beaty, B J
• Format: Journal Article
• Language: English
• Published: England 01.03.2003
• Subjects: Animals; Cell Line; Cercopithecus aethiops; Culicidae - genetics; Culicidae - immunology; Culicidae - virology; Gene Expression Regulation - immunology; Interferon-alpha - genetics; Interferon-beta - genetics; Mice; New Jersey; Polymerase Chain Reaction; Rhabdoviridae Infections - genetics; Rhabdoviridae Infections - physiopathology; Rhabdoviridae Infections - virology; RNA, Messenger - genetics; RNA, Viral - genetics; Vero Cells; Vesiculovirus - genetics; Vesiculovirus - isolation & purification; Vesiculovirus - physiology; Virus Replication - physiology; New Jersey

The sensitivity of vesicular stomatitis (VS) viruses to interferon (IFN)-mediated antiviral effects has been well documented. Previous studies in our laboratory have shown the ability of mosquito saliva to enhance vesicular stomatitis New Jersey (VSNJ) virus infection in mice. To investigate the eff...