Effects of micronutrients on placental function: evidence from clinical studies to animal models

• Published in: Reproduction (Cambridge, England) Vol. 156; no. 3; pp. R69 - R82
• Main Authors: Baker, Bernadette C, Hayes, Dexter JL, Jones, Rebecca L
• Format: Journal Article
• Language: English
• Published: England Bioscientifica Ltd 01.09.2018
• Subjects: Animals; Dietary Supplements; Female; Fetal Development; Folic Acid - administration & dosage; Folic Acid - physiology; Folic Acid Deficiency - complications; Humans; Infant, Newborn; Iron - deficiency; Iron - physiology; Iron, Dietary - administration & dosage; Micronutrients - administration & dosage; Micronutrients - deficiency; Micronutrients - physiology; Models, Animal; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Randomized Controlled Trials as Topic; Review; Trophoblasts; Vitamin A - administration & dosage; Vitamin A - physiology; Vitamin A Deficiency - complications; Vitamin B 12 - administration & dosage; Vitamin B 12 - physiology; Vitamin B 12 Deficiency - complications; Vitamin D - administration & dosage; Vitamin D - physiology; Vitamin D Deficiency - complications

Micronutrient deficiencies are common in pregnant women due to low dietary intake and increased requirements for fetal development. Low maternal micronutrient status is associated with a range of pregnancy pathologies involving placental dysfunction, including fetal growth restriction (FGR), small-f...