Gut microbiota modulates COPD pathogenesis: role of anti-inflammatory Parabacteroides goldsteinii lipopolysaccharide - Lai, Hsin-Chih; Lin, Tzu-Lung; Chen, Ting-Wen; Kuo, Yu-Lun; Chang, Chih-Jung; Wu, Tsung-Ru; Shu, Ching-Chung; Tsai, Ying-Huang; Swift, Simon; Lu, Chia-Chen (Gut, 2022)
Keywords: Animals; Antibiotics; Bacteroidetes - isolation & purification; Chronic obstructive pulmonary disease; Cigarette smoking; Clinical medicine; Digestive system; Discriminant analysis; Disease Models, Animal; Experiments; Fecal Microbiota Transplantation; Flow cytometry; Gastrointestinal Microbiome - physiology; Gastrointestinal tract; Gene expression; Genomes; Gut microbiota; Histopathology; immunology; Inflammation; intestinal microbiology; Intestinal microflora; Laboratory animals; Lavage; Lipopolysaccharides; Lipopolysaccharides - metabolism; Lung diseases; Metabolomics; Mice; Mice, Inbred C57BL; Microbiota; Mitochondria; Mortality; Obstructive lung disease; Oral administration; Parabacteroides; Pathogenesis; Pulmonary Disease, Chronic Obstructive - etiology; Pulmonary Disease, Chronic Obstructive - metabolism; Pulmonary Disease, Chronic Obstructive - pathology; Respiratory tract; Signal transduction; Smoking; TLR4 protein; Toll-like receptors; Transplantation; Tumor necrosis factor-TNF; Variance analysis; United States--US; Taiwan; intestinal microbiology; immunology