Temporal lobe epilepsy lateralisation and surgical outcome prediction using diffusion imaging

• Published in: Journal of neurology, neurosurgery and psychiatry Vol. 93; no. 6; pp. 599 - 608
• Main Authors: Johnson, Graham W., Cai, Leon Y., Narasimhan, Saramati, González, Hernán F. J., Wills, Kristin E., Morgan, Victoria L., Englot, Dario J.
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd 01.06.2022; BMJ Publishing Group LTD
• Subjects: Artificial intelligence; Clinical decision making; Convulsions & seizures; Drug resistance; Electroencephalography; Epilepsy; epilepsy, surgery; Epilepsy, Temporal Lobe - diagnostic imaging; Epilepsy, Temporal Lobe - surgery; Female; Humans; image analysis; Localization; Machine learning; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; neurosurgery; Seizures; Surgery; Surgical outcomes; Tomography; Treatment Outcome; White Matter - pathology; neurosurgery; image analysis; epilepsy, surgery

ObjectiveWe sought to augment the presurgical workup of medically refractory temporal lobe epilepsy by creating a supervised machine learning technique that uses diffusion-weighted imaging to classify patient-specific seizure onset laterality and surgical outcome.Methods151 subjects were included in...