Gene expression changes in medical workers exposed to radiation

• Published in: Radiation research Vol. 172; no. 4; p. 500
• Main Authors: Morandi, Elena, Severini, Cinzia, Quercioli, Daniele, Perdichizzi, Stefania, Mascolo, Maria Grazia, Horn, Wolfango, Vaccari, Monica, Nucci, Maria Concetta, Lodi, Vittorio, Violante, Francesco Saverio, Bolognesi, Claudia, Grilli, Sandro, Silingardi, Paola, Colacci, Annamaria
• Format: Journal Article
• Language: English
• Published: United States 01.10.2009
• Subjects: Adult; Female; Gene Expression Profiling; Gene Expression Regulation - radiation effects; Health Personnel; Humans; Male; Middle Aged; Occupational Exposure - adverse effects; Oligonucleotide Array Sequence Analysis; Radiation Dosage; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment

The use of nuclear resources for medical purposes causes considerable concern about occupational exposure. Nevertheless, little information is available regarding the effects of low-dose irradiations protracted over time. We used oligomicroarrays to identify the genes that are transcriptionally regu...