Bedside cerebral microdialysis monitoring of delayed cerebral hypoperfusion in comatose patients with poor grade aneurysmal subarachnoid haemorrhage

• Published in: Journal of neurology, neurosurgery and psychiatry Vol. 88; no. 4; pp. 332 - 338
• Main Authors: Patet, Camille, Quintard, Hervé, Zerlauth, Jean-Baptiste, Maibach, Thomas, Carteron, Laurent, Suys, Tamarah, Bouzat, Pierre, Bervini, David, Levivier, Marc, Daniel, Roy T, Eckert, Philippe, Meuli, Reto, Oddo, Mauro
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group LTD 01.04.2017
• Subjects: Adult; Aged; Anesthesia; Aneurysm, Ruptured - diagnosis; Aneurysm, Ruptured - physiopathology; Aneurysms; Biomarkers; Blood Glucose - metabolism; Brain - physiopathology; Brain Ischemia - diagnosis; Brain Ischemia - physiopathology; Cohort Studies; Coma; Coma - diagnosis; Coma - physiopathology; Critical Care; Female; Follow-Up Studies; Glucose; Hemorrhage; Humans; Intensive care; Intracranial Aneurysm - diagnosis; Intracranial Aneurysm - physiopathology; Lactic Acid - metabolism; Male; Medical imaging; Microdialysis; Middle Aged; Monitoring, Physiologic; Oxygen Consumption - physiology; Patients; Physiology; Point-of-Care Testing; Prospective Studies; Pyruvic Acid - metabolism; Subarachnoid Hemorrhage - diagnosis; Subarachnoid Hemorrhage - physiopathology; Tomography, X-Ray Computed; Traumatic brain injury; Veins & arteries

BackgroundDelayed cerebral ischaemia (DCI) is frequent after poor grade aneurysmal subarachnoid haemorrhage (SAH). Owing to the limited accuracy of clinical examination, DCI diagnosis is often based on multimodal monitoring. We examined the value of cerebral microdialysis (CMD) in this setting.Metho...