Repeated administration of ghrelin to patients with functional dyspepsia: its effects on food intake and appetite

• Published in: European journal of endocrinology Vol. 158; no. 4; pp. 491 - 498
• Main Authors: Akamizu, Takashi, Iwakura, Hiroshi, Ariyasu, Hiroyuki, Hosoda, Hiroshi, Murayama, Toshinori, Yokode, Masayuki, Teramukai, Satoshi, Seno, Hiroshi, Chiba, Tsutomu, Noma, Shunichi, Nakai, Yoshikatsu, Fukunaga, Mikihiko, Nakai, Yoshihide, Kangawa, Kenji, FD Clinical Study Team
• Format: Journal Article
• Language: English
• Published: Colchester BioScientifica 01.04.2008; Portland Press
• Subjects: Adult; Algorithms; Anorexia - drug therapy; Anorexia - etiology; Appetite - drug effects; Biological and medical sciences; Body Composition - drug effects; Body Mass Index; Clinical Studies; Drug Administration Schedule; Dyspepsia - blood; Dyspepsia - complications; Dyspepsia - drug therapy; Eating - drug effects; Endocrinopathies; Female; Fundamental and applied biological sciences. Psychology; Gastroenterology. Liver. Pancreas. Abdomen; Ghrelin - administration & dosage; Ghrelin - adverse effects; Ghrelin - blood; Ghrelin - pharmacology; Humans; Infusion Pumps; Male; Medical sciences; Other diseases. Semiology; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Treatment Outcome; Vertebrates: endocrinology; Appetite; Human; Health food; Food intake; Dyspepsia; Ghrelin; Digestive diseases; Patient; Endocrinology; Appetite stimulant

BackgroundGhrelin plays a major role in the regulation of food intake (FI), which makes it a strong candidate for the treatment of anorexia.ObjectiveWe attempted to evaluate the clinical response to repeated ghrelin administration in patients with anorexia caused by functional disorders, such as fun...