Major CYP450 Polymorphism among Saudi Patients

• Published in: Drug metabolism letters Vol. 14; no. 1; p. 17
• Main Author: Almeman, Ahmad A
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 2021
• Subjects: Adolescent; Adult; Aged; ATP Binding Cassette Transporter, Subfamily B - genetics; Cytochrome P-450 CYP2C19 - genetics; Cytochrome P-450 CYP2C9 - genetics; Cytochrome P-450 CYP2D6 - genetics; Cytochrome P-450 Enzyme System - genetics; Gene Frequency; Genetics, Population; Genotype; Humans; Middle Aged; Polymorphism, Genetic; Saudi Arabia; Young Adult; Saudi Arabia; CYP2C9; MDR1; CYP2D6; Saudis; polymorphism; CYP2C19; Cytochrome P450 (CYP)

Cytochrome P450 (CYP) contributes to a huge collection of medicinal products' Phase I metabolization. We aimed to summarize and investigate the current evidence regarding the frequency of CYP2D6, CYP2C9, CYP2C19, and MDR1 in Saudi Arabia. A computerized search in four databases was done using t...