Biomarker Assays for Personalised Stroke Risk Assessment in Atrial Fibrillation

• Published in: Cardiovascular & hematological disorders drug targets Vol. 17; no. 1; p. 58
• Main Authors: Hall, Angela, Simpson, Rupert F G, Mitchell, Andrew R J
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 2017
• Subjects: Animals; Atrial Fibrillation - blood; Atrial Fibrillation - complications; Biomarkers - analysis; Biomarkers - blood; Fibrin Fibrinogen Degradation Products - analysis; Humans; Natriuretic Peptide, Brain - analysis; Natriuretic Peptide, Brain - blood; Precision Medicine; Prognosis; Risk Assessment; Risk Factors; Stroke - blood; Stroke - diagnosis; Stroke - etiology; Troponin C - analysis; Troponin C - blood; D-dimers; troponin; BNP; Atrial fibrillation; biomarkers; personalised medicine; stroke risk

Atrial fibrillation is a well-known independent risk factor for stroke yet there is no international consensus on guidelines regarding the introduction of anticoagulation in patients deemed at intermediate risk (e.g. CHA2DS2-VASc of 1). The evolution of cardiac biomarkers such as highly sensitive tr...