THE EFFECT OF OVARIAN STEROIDS ON HYPOTHALAMIC THRESHOLDS FOR OVULATION IN THE FEMALE RAT

• Published in: Journal of endocrinology Vol. 49; no. 3; pp. 421 - 429
• Main Authors: McDonald, P G, Gilmore, D P
• Format: Journal Article
• Language: English
• Published: England BioScientifica 01.03.1971
• Subjects: Animals; Electric Stimulation; Electrodes; Estradiol - pharmacology; Estrus; Fallopian Tubes; Female; Hypothalamus - drug effects; Ovulation - drug effects; Ovum; Pregnancy; Progesterone - pharmacology; Rats

Electrochemical stimulation of the basal and preoptic hypothalamus, under sodium pentobarbitone anaesthesia, was carried out on the day of pro-oestrus in normal cycling and in ovarian hormone-treated female rats. Control rats ovulated in response to 25, 50 and 100 μA for 60 s in the median eminence...