Is confirmatory testing of Roche cobas 4800 CT/NG test Neisseria gonorrhoeae positive samples required? Comparison of the Roche cobas 4800 CT/NG test with an opa/pap duplex assay for the detection of N gonorrhoeae

• Published in: Sexually transmitted infections Vol. 90; no. 4; pp. 303 - 308
• Main Authors: Perry, Michael D, Jones, Rachel N, Corden, Sally A
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group LTD 01.06.2014
• Subjects: Bacterial Outer Membrane Proteins - genetics; Colony Count, Microbial; DNA, Bacterial - analysis; Females; Gonorrhea; Gonorrhea - diagnosis; Humans; Microscopy; Neisseria gonorrhoeae - genetics; Neisseria gonorrhoeae - isolation & purification; Nucleic Acid Amplification Techniques; Patients; Pseudogenes - genetics; Repetitive Sequences, Nucleic Acid - genetics; Sensitivity and Specificity; Sexual health; Urine; United Kingdom > UK; Wales; PCR; Diagnosis; Neisseria Gonorrhoea

Objectives Recently marketed nucleic acid amplification tests (NAAT) for the detection of Neisseria gonorrhoeae (NG) have improved specificity over previous generation assays. A study to assess the necessity for confirmation of Roche cobas 4800 NG positive samples was undertaken by the Public Health...