TGF-β1 induces human alveolar epithelial to mesenchymal cell transition (EMT)

• Published in: Respiratory research Vol. 6; no. 1; p. 56
• Main Authors: Kasai, Hidenori, Allen, Jeremy T, Mason, Roger M, Kamimura, Takashi, Zhang, Zhi
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 09.06.2005; BioMed Central; BMC

Abstract Background Fibroblastic foci are characteristic features in lung parenchyma of patients with idiopathic pulmonary fibrosis (IPF). They comprise aggregates of mesenchymal cells which underlie sites of unresolved epithelial injury and are associated with progression of fibrosis. However, the...