Nanotechnology in Drug Delivery: An Overview of Developing the Blood Brain Barrier

• Published in: Current neurovascular research Vol. 21; no. 4; p. 347
• Main Authors: Dash, Rasmita, Samanta, Subhankar, Jena, Bikash Ranjan, Pradhan, Soumyaranjan
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 2025
• Subjects: Animals; Blood-Brain Barrier - drug effects; Blood-Brain Barrier - physiology; Drug Delivery Systems - methods; Humans; Nanoparticles; Nanotechnology - methods; blood brain barrier; nanomaterials; drug delivery; Endothelial cells; nanocarriers; neurological disorder

The close connection between the brain microvascular endothelial cells (BMECs) that are enclosed within this barrier is the result of an intracellular junction, which is responsible for the constricted connection. The regulation and control of drug delivery systems both require nanoparticles, which...