Electroacupuncture Serum Protects against Blood-brain Barrier Damage after Ischemic Stroke by Regulating Pericytes in vitro

• Published in: Current neurovascular research Vol. 21; no. 4; p. 491
• Main Authors: Zhang, Hanrui, Lyv, Hequn, Feng, Yaoting, Peng, Yongjun
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 2025
• Subjects: Animals; Apoptosis - physiology; Blood-Brain Barrier - drug effects; Blood-Brain Barrier - metabolism; Blood-Brain Barrier - pathology; Cells, Cultured; Coculture Techniques; Electroacupuncture - methods; Endothelial Cells; Ischemic Stroke - pathology; Ischemic Stroke - therapy; Male; Pericytes - metabolism; Rats; Rats, Sprague-Dawley; Serum; Electroacupuncture serum; blood-brain barrier; hypoxia; oxygen-glucose deprivation/reoxygenation; pericyte; ischemic stroke

Electroacupuncture (EA) exerts a protective role in Blood-brain Barrier (BBB) damage after ischemic stroke, but whether this effect involves the regulation of the pericytes is unclear. The BBB models were established with brain microvascular endothelial cells (BMECs) and pericytes, and the co-cultur...