Monocentric study of 112 consecutive patients with childhood onset GH deficiency around and after transition

• Published in: European journal of endocrinology Vol. 169; no. 5; pp. 587 - 596
• Main Authors: Courtillot, Carine, Baudoin, Roselyne, Du Souich, Tatiana, Saatdjian, Lucile, Tejedor, Isabelle, Pinto, Graziella, Léger, Juliane, Polak, Michel, Golmard, Jean-Louis, Touraine, Philippe
• Format: Journal Article
• Language: English
• Published: Bristol BioScientifica 01.11.2013
• Subjects: Absorptiometry, Photon; Adolescent; Adult; Aging - physiology; Biological and medical sciences; Bone Density; Child; Clinical Study; Cohort Studies; Endocrinopathies; Female; Follow-Up Studies; Fundamental and applied biological sciences. Psychology; General aspects; Human Growth Hormone - deficiency; Human Growth Hormone - therapeutic use; Humans; Hypopituitarism - complications; Insulin-Like Growth Factor I - metabolism; Lipids - blood; Male; Medical sciences; Multivariate Analysis; Pituitary Function Tests; Recombinant Proteins - therapeutic use; Retrospective Studies; Vertebrates: endocrinology; Young Adult; Endocrinopathy; Human; Somatotropin; Adenohypophyseal hormone; Deficiency; Transition; Patient; Child; Endocrinology

ObjectivesOur aim was to analyze a large cohort of childhood onset GH deficiency (CO-GHD) adults from a unique adult center, in order to analyze their clinical management and to study the metabolic and bone status in relation to GHD and to the other pituitary deficits, and to evaluate these paramete...