Headache and Intracranial Aneurysm: A Bidirectional Mendelian Randomization Study

• Published in: Current neurovascular research
• Main Authors: Ren, Chunlin, Gao, Qian, Li, Xinmin, Yang, Fangjie, Wang, Jing, Guo, Pengxue, Duan, Zhenfei, Kong, YuTing, Bi, MengYao, Chen, Lidian, Zhang, Yasu
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 04.06.2025
• Subjects: Headache; causal link; migraine; intracranial aneurysm; single nucleotide polymorphism; mendelian randomization

Headaches affect up to 95% of individuals during their lifetime and are a major global cause of disability. Intracranial Aneurysm (IA) is a cerebrovascular disorder affecting approximately 3.2% of the general population. Observational studies have suggested an association between headaches and IA, b...