Search for clastogenic factors in the plasma of locally irradiated individuals

• Published in: Radiation research Vol. 177; no. 3; p. 298
• Main Authors: Lindholm, C, Acheva, A, Koivistoinen, A, Perälä, M, Heinävaara, S, Jahns, J, Salomaa, S, Hildebrandt, G
• Format: Journal Article
• Language: English
• Published: United States 01.03.2012
• Subjects: Adult; Aged; Aged, 80 and over; Chromatids - drug effects; Chromatids - genetics; Chromosome Aberrations - drug effects; Female; Histones - metabolism; Humans; Logistic Models; Lymphocytes - cytology; Lymphocytes - drug effects; Lymphocytes - metabolism; Male; Middle Aged; Mutagens - metabolism; Mutagens - pharmacology; Plasma - metabolism; Plasma - radiation effects; Radioactive Hazard Release; Young Adult

In studies reported in the 1960s and in several investigations since, plasma from irradiated individuals was shown to induce chromosomal aberrations when transferred into normal blood cultures. In the present study, the aim was to investigate the occurrence of these clastogenic factors (CF) using ma...