Weekend versus weekday hospitalization and clinical outcomes in atrial fibrillation patients with and without stroke
PurposeThe relation between hospitalization timing and risk of clinical outcomes among patients with atrial fibrillation (AF) with and without stroke remained undetermined.MethodsRehospitalization due to AF, cardiovascular (CV) death and all-cause mortality were the outcomes of interest in this stud...
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| Published in | Postgraduate medical journal Vol. 99; no. 1171; pp. 470 - 475 |
|---|---|
| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
England
The Fellowship of Postgraduate Medicine
08.06.2023
Oxford University Press |
| Subjects | |
| Online Access | Get full text |
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| Abstract | PurposeThe relation between hospitalization timing and risk of clinical outcomes among patients with atrial fibrillation (AF) with and without stroke remained undetermined.MethodsRehospitalization due to AF, cardiovascular (CV) death and all-cause mortality were the outcomes of interest in this study. Multivariable Cox proportional hazard model was applied to estimate the adjusted hazard ratio (HR) and 95% confidence interval (CI).ResultsWhile considering patients with AF hospitalized during weekdays without stroke as the reference group, patients with AF hospitalized during weekends with stroke had the risk of AF rehospitalization, CV death and all-cause death by 1.48 (95% CI 1.44 to 1.51), 1.77 (95% CI 1.71 to 1.83) and 1.17 (95% CI 1.15 to 1.19) times, respectively.ConclusionPatients with AF hospitalized during weekends with stroke had the worst clinical outcomes. |
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| AbstractList | The relation between hospitalization timing and risk of clinical outcomes among patients with atrial fibrillation (AF) with and without stroke remained undetermined.
Rehospitalization due to AF, cardiovascular (CV) death and all-cause mortality were the outcomes of interest in this study. Multivariable Cox proportional hazard model was applied to estimate the adjusted hazard ratio (HR) and 95% confidence interval (CI).
While considering patients with AF hospitalized during weekdays without stroke as the reference group, patients with AF hospitalized during weekends with stroke had the risk of AF rehospitalization, CV death and all-cause death by 1.48 (95% CI 1.44 to 1.51), 1.77 (95% CI 1.71 to 1.83) and 1.17 (95% CI 1.15 to 1.19) times, respectively.
Patients with AF hospitalized during weekends with stroke had the worst clinical outcomes. The relation between hospitalization timing and risk of clinical outcomes among patients with atrial fibrillation (AF) with and without stroke remained undetermined.PURPOSEThe relation between hospitalization timing and risk of clinical outcomes among patients with atrial fibrillation (AF) with and without stroke remained undetermined.Rehospitalization due to AF, cardiovascular (CV) death and all-cause mortality were the outcomes of interest in this study. Multivariable Cox proportional hazard model was applied to estimate the adjusted hazard ratio (HR) and 95% confidence interval (CI).METHODSRehospitalization due to AF, cardiovascular (CV) death and all-cause mortality were the outcomes of interest in this study. Multivariable Cox proportional hazard model was applied to estimate the adjusted hazard ratio (HR) and 95% confidence interval (CI).While considering patients with AF hospitalized during weekdays without stroke as the reference group, patients with AF hospitalized during weekends with stroke had the risk of AF rehospitalization, CV death and all-cause death by 1.48 (95% CI 1.44 to 1.51), 1.77 (95% CI 1.71 to 1.83) and 1.17 (95% CI 1.15 to 1.19) times, respectively.RESULTSWhile considering patients with AF hospitalized during weekdays without stroke as the reference group, patients with AF hospitalized during weekends with stroke had the risk of AF rehospitalization, CV death and all-cause death by 1.48 (95% CI 1.44 to 1.51), 1.77 (95% CI 1.71 to 1.83) and 1.17 (95% CI 1.15 to 1.19) times, respectively.Patients with AF hospitalized during weekends with stroke had the worst clinical outcomes.CONCLUSIONPatients with AF hospitalized during weekends with stroke had the worst clinical outcomes. Purpose The relation between hospitalization timing and risk of clinical outcomes among patients with atrial fibrillation (AF) with and without stroke remained undetermined. Methods Rehospitalization due to AF, cardiovascular (CV) death and all-cause mortality were the outcomes of interest in this study. Multivariable Cox proportional hazard model was applied to estimate the adjusted hazard ratio (HR) and 95% confidence interval (CI). Results While considering patients with AF hospitalized during weekdays without stroke as the reference group, patients with AF hospitalized during weekends with stroke had the risk of AF rehospitalization, CV death and all-cause death by 1.48 (95% CI 1.44 to 1.51), 1.77 (95% CI 1.71 to 1.83) and 1.17 (95% CI 1.15 to 1.19) times, respectively. Conclusion Patients with AF hospitalized during weekends with stroke had the worst clinical outcomes. PurposeThe relation between hospitalization timing and risk of clinical outcomes among patients with atrial fibrillation (AF) with and without stroke remained undetermined.MethodsRehospitalization due to AF, cardiovascular (CV) death and all-cause mortality were the outcomes of interest in this study. Multivariable Cox proportional hazard model was applied to estimate the adjusted hazard ratio (HR) and 95% confidence interval (CI).ResultsWhile considering patients with AF hospitalized during weekdays without stroke as the reference group, patients with AF hospitalized during weekends with stroke had the risk of AF rehospitalization, CV death and all-cause death by 1.48 (95% CI 1.44 to 1.51), 1.77 (95% CI 1.71 to 1.83) and 1.17 (95% CI 1.15 to 1.19) times, respectively.ConclusionPatients with AF hospitalized during weekends with stroke had the worst clinical outcomes. |
| Author | Lin, Cheng-Li Hu, Wei Syun |
| Author_xml | – sequence: 1 givenname: Wei Syun orcidid: 0000-0003-2478-923X surname: Hu fullname: Hu, Wei Syun email: weisyunhu@gmail.com organization: Division of Cardiovascular Medicine, Department of Medicine, China Medical University Hospital, Taichung, Taiwan – sequence: 2 givenname: Cheng-Li surname: Lin fullname: Lin, Cheng-Li organization: School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35512984$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.7717/peerj.6211 10.1016/j.amjcard.2012.03.011 10.1016/j.jss.2015.04.047 10.1136/heartjnl-2020-317455 10.1016/S0140-6736(09)60040-4 10.1016/j.ijcard.2015.07.075 10.1016/S1474-4422(15)70027-X 10.1016/j.pnpbp.2019.01.013 10.1016/j.jacc.2014.06.1203 10.1161/STROKEAHA.116.013880 10.1016/j.amjmed.2016.02.029 10.1097/HPC.0000000000000128 10.1016/j.cjca.2018.08.036 10.1002/pds.2087 10.1093/ehjcvp/pvab047 10.1161/STROKEAHA.115.012004 10.1161/CIRCULATIONAHA.115.019794 10.1161/STROKEAHA.114.006070 10.4070/kcj.2019.0367 10.1016/j.jstrokecerebrovasdis.2013.05.015 10.1136/bmjopen-2017-020065 |
| ContentType | Journal Article |
| Copyright | Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ. 2022 Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ. The Author(s) 2022. Published by Oxford University Press on behalf of Postgraduate Medical Journal. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com The Author(s) 2022. Published by Oxford University Press on behalf of Postgraduate Medical Journal. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. |
| Copyright_xml | – notice: Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ. – notice: 2022 Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ. – notice: The Author(s) 2022. Published by Oxford University Press on behalf of Postgraduate Medical Journal. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com – notice: The Author(s) 2022. Published by Oxford University Press on behalf of Postgraduate Medical Journal. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. |
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| References_xml | – volume: 7 year: 2019 ident: R9 article-title: Outcomes of hospitalizations with atrial fibrillation-flutter on a weekday versus weekend: an analysis from a 2014 nationwide inpatient sample publication-title: PeerJ doi: 10.7717/peerj.6211 – volume: 110 start-page: 208 year: 2012 ident: R11 article-title: Comparison of outcomes of weekend versus weekday admissions for atrial fibrillation publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2012.03.011 – volume: 198 start-page: 267 year: 2015 ident: R2 article-title: Predicting postoperative atrial fibrillation using CHA2DS2-VASc scores publication-title: J Surg Res doi: 10.1016/j.jss.2015.04.047 – volume: 107 start-page: 99 year: 2021 ident: R16 article-title: Fibrosis, atrial fibrillation and stroke: clinical updates and emerging mechanistic models publication-title: Heart doi: 10.1136/heartjnl-2020-317455 – volume: 373 start-page: 155 year: 2009 ident: R15 article-title: Mechanisms of thrombogenesis in atrial 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ischemic stroke: evidence supporting the neurogenic hypothesis publication-title: J Stroke Cerebrovasc Dis doi: 10.1016/j.jstrokecerebrovasdis.2013.05.015 – volume: 110 start-page: 208 year: 2012 ident: 2023060916584540800_R11 article-title: Comparison of outcomes of weekend versus weekday admissions for atrial fibrillation publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2012.03.011 – volume: 14 start-page: 377 year: 2015 ident: 2023060916584540800_R5 article-title: Diagnosis of atrial fibrillation after stroke and transient ischaemic attack: a systematic review and meta-analysis publication-title: Lancet Neurol doi: 10.1016/S1474-4422(15)70027-X – volume: 107 start-page: 99 year: 2021 ident: 2023060916584540800_R16 article-title: Fibrosis, atrial fibrillation and stroke: clinical updates and emerging mechanistic models publication-title: Heart doi: 10.1136/heartjnl-2020-317455 – volume: 47 start-page: 2462 year: 2016 ident: 2023060916584540800_R20 article-title: Validation of a modified CHA2DS2-VASc score for stroke risk stratification in Asian patients with atrial fibrillation: a nationwide cohort study publication-title: Stroke doi: 10.1161/STROKEAHA.116.013880 – volume: 20 start-page: 236 year: 2011 ident: 2023060916584540800_R21 article-title: Validation of the National health insurance research database with ischemic stroke cases in Taiwan publication-title: Pharmacoepidemiol Drug Saf doi: 10.1002/pds.2087 – volume: 133 start-page: 1540 year: 2016 ident: 2023060916584540800_R18 article-title: Use of oral anticoagulants for stroke prevention in patients with atrial fibrillation who have a history of intracranial hemorrhage publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.115.019794 – volume: 129 start-page: 843 year: 2016 ident: 2023060916584540800_R1 article-title: Usefulness of CHADS2 and CHA2DS2-VASc scores in the prediction of new-onset atrial fibrillation: a population-based study publication-title: Am J Med doi: 10.1016/j.amjmed.2016.02.029 – year: 2020 ident: 2023060916584540800_R12 article-title: Comparison of new-onset diabetes mellitus among patients with atrial fibrillation or atrial flutter publication-title: Korean Circ J – volume: 92 start-page: 470 year: 2019 ident: 2023060916584540800_R13 article-title: Suicide attempt in patients with atrial fibrillation - A nationwide cohort study publication-title: Prog Neuropsychopharmacol Biol Psychiatry doi: 10.1016/j.pnpbp.2019.01.013 – volume: 34 start-page: 1503 year: 2018 ident: 2023060916584540800_R17 article-title: The multiple causes of stroke in atrial fibrillation: thinking broadly publication-title: Can J Cardiol doi: 10.1016/j.cjca.2018.08.036 – volume: 198 start-page: 267 year: 2015 ident: 2023060916584540800_R2 article-title: Predicting postoperative atrial fibrillation using CHA2DS2-VASc scores publication-title: J Surg Res doi: 10.1016/j.jss.2015.04.047 – volume: 8 year: 2018 ident: 2023060916584540800_R3 article-title: Role of CHA2DS2-VASc score in predicting new-onset atrial fibrillation in patients with type 2 diabetes mellitus with and without hyperosmolar hyperglycaemic state: real-world data from a nationwide cohort publication-title: BMJ Open doi: 10.1136/bmjopen-2017-020065 – volume: 17 start-page: 111 year: 2018 ident: 2023060916584540800_R8 article-title: Atrial fibrillation and the weekend effect regarding cardioversion, length of stay, readmission, and mortality publication-title: Crit Pathw Cardiol doi: 10.1097/HPC.0000000000000128 – volume: 7 year: 2019 ident: 2023060916584540800_R9 article-title: Outcomes of hospitalizations with atrial fibrillation-flutter on a weekday versus weekend: an analysis from a 2014 nationwide inpatient sample publication-title: PeerJ doi: 10.7717/peerj.6211 – volume: 373 start-page: 155 year: 2009 ident: 2023060916584540800_R15 article-title: Mechanisms of thrombogenesis in atrial fibrillation: Virchow's triad revisited publication-title: Lancet doi: 10.1016/S0140-6736(09)60040-4 – ident: 2023060916584540800_R7 article-title: National health insurance research database – volume: 28 year: 2021 ident: 2023060916584540800_R10 article-title: Weekend versus weekday admission and clinical outcomes in heart failure patients with and without atrial fibrillation in Taiwan publication-title: Eur Heart J Cardiovasc Pharmacother – volume: 47 start-page: 895 year: 2016 ident: 2023060916584540800_R14 article-title: Atrial fibrillation and mechanisms of stroke: time for a new model publication-title: Stroke doi: 10.1161/STROKEAHA.115.012004 |
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| Snippet | PurposeThe relation between hospitalization timing and risk of clinical outcomes among patients with atrial fibrillation (AF) with and without stroke remained... The relation between hospitalization timing and risk of clinical outcomes among patients with atrial fibrillation (AF) with and without stroke remained... Purpose The relation between hospitalization timing and risk of clinical outcomes among patients with atrial fibrillation (AF) with and without stroke remained... |
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| StartPage | 470 |
| SubjectTerms | Alcohol Anticoagulants Cardiac arrhythmia Cardiovascular disease Chronic obstructive pulmonary disease Clinical outcomes Comorbidity Coronary vessels Diabetes Heart failure Hospitalization Hypertension Illnesses Kidney diseases Obesity Original research Software Stroke Vein & artery diseases |
| Title | Weekend versus weekday hospitalization and clinical outcomes in atrial fibrillation patients with and without stroke |
| URI | https://pmj.bmj.com/content/early/2022/05/04/postgradmedj-2022-141684.full https://www.ncbi.nlm.nih.gov/pubmed/35512984 https://www.proquest.com/docview/2666541894 https://www.proquest.com/docview/3240585668 https://www.proquest.com/docview/2824692373 |
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