Is idiopathic hirsutism (IH) really idiopathic? mRNA expressions of skin steroidogenic enzymes in women with IH

• Published in: European journal of endocrinology Vol. 173; no. 4; pp. 447 - 454
• Main Authors: Taheri, Serpil, Zararsiz, Gokmen, Karaburgu, Sulbiye, Borlu, Murat, Ozgun, Mahmut Tuncay, Karaca, Zuleyha, Tanriverdi, Fatih, Dundar, Munis, Kelestimur, Fahrettin, Unluhizarci, Kursad
• Format: Journal Article
• Language: English
• Published: England Bioscientifica Ltd 01.10.2015
• Subjects: Abdomen; Adolescent; Adult; Androgens - biosynthesis; Androgens - metabolism; Arm; Case-Control Studies; Clinical Study; Estradiol Dehydrogenases - genetics; Female; Hirsutism - enzymology; Hirsutism - genetics; Humans; Interleukin-6 - genetics; RNA, Messenger - blood; RNA, Messenger - metabolism; Skin - enzymology; Skin - metabolism; Steryl-Sulfatase - genetics; Young Adult

ObjectiveHirsutism results from hyperandrogenemia and/or exaggerated androgen responsiveness. Among various causes of hirsutism, some patients do not exhibit androgen excess which is called idiopathic hirsutism (IH). The pathogenesis of IH could not so far be clearly established.DesignTo investigate...