Falsely elevated capillary glucose and ketone levels and use of skin lightening creams
Hand washing before glucose and ketone fingerprick testing prevents false results in users of skin lightening cosmetics
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Published in | BMJ (Online) Vol. 351; no. 8022; p. h3879 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
England
British Medical Journal Publishing Group
29.07.2015
BMJ Publishing Group LTD |
Subjects | |
Online Access | Get full text |
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Abstract | Hand washing before glucose and ketone fingerprick testing prevents false results in users of skin lightening cosmetics |
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AbstractList | Hand washing before glucose and ketone fingerprick testing prevents false results in users of skin lightening cosmetics Hyperglycaemia associated with ketosis reflects severe insulin deficiency that mandates immediate insulin therapy. Point-of-care devices to measure capillary glucose have become essential in diabetes management.1 Management of hyperglycaemic crisis has also been improved by the measurement of ß-hydroxybutyrate in a fingerprick blood specimen. The method is quick, accurate, and reliable,2 3 4 and recommended to medical care providers and patients.2 5 6 Here we report two cases of misleadingly high capillary glucose and ketone measurements that could have been prevented by careful hand washing. We also identify the chemical compound, hydroquinone, that interferes with capillary results. |
Author | Choukem, Siméon-Pierre Garnier, Jean-Pierre Bouché, Clara H Gautier, Jean-François |
Author_xml | – sequence: 1 givenname: Clara H surname: Bouché fullname: Bouché, Clara H email: jean-francois.gautier@lrb.aphp.fr organization: Biochemistry Laboratory, Saint-Louis University Hospital, Assistance Publique - Hôpitaux de Paris, University Paris Descartes, 75010 Paris, France – sequence: 2 givenname: Jean-Pierre surname: Garnier fullname: Garnier, Jean-Pierre email: jean-francois.gautier@lrb.aphp.fr organization: Biochemistry Laboratory, Saint-Louis University Hospital, Assistance Publique - Hôpitaux de Paris, University Paris Descartes, 75010 Paris, France – sequence: 3 givenname: Siméon-Pierre surname: Choukem fullname: Choukem, Siméon-Pierre email: jean-francois.gautier@lrb.aphp.fr organization: Biochemistry Laboratory, Saint-Louis University Hospital, Assistance Publique - Hôpitaux de Paris, University Paris Descartes, 75010 Paris, France – sequence: 4 givenname: Jean-François surname: Gautier fullname: Gautier, Jean-François email: jean-francois.gautier@lrb.aphp.fr organization: Biochemistry Laboratory, Saint-Louis University Hospital, Assistance Publique - Hôpitaux de Paris, University Paris Descartes, 75010 Paris, France |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26223684$$D View this record in MEDLINE/PubMed |
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Snippet | Hand washing before glucose and ketone fingerprick testing prevents false results in users of skin lightening cosmetics Hyperglycaemia associated with ketosis reflects severe insulin deficiency that mandates immediate insulin therapy. Point-of-care devices to measure capillary... |
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SubjectTerms | 3-Hydroxybutyric Acid - analysis 3-Hydroxybutyric Acid - blood Adult Biomarkers - analysis Biomarkers - blood Blood Glucose - analysis Blood Glucose - metabolism Capillaries Cosmetics Diabetes False Positive Reactions Female Glucose Hand Disinfection Humans Hydroquinones - analysis Hyperglycemia - blood Hyperglycemia - diagnosis Insulin LESSON OF THE WEEK Patients Skin Skin Lightening Preparations - adverse effects |
Title | Falsely elevated capillary glucose and ketone levels and use of skin lightening creams |
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