Falsely elevated capillary glucose and ketone levels and use of skin lightening creams

Hand washing before glucose and ketone fingerprick testing prevents false results in users of skin lightening cosmetics

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Published inBMJ (Online) Vol. 351; no. 8022; p. h3879
Main Authors Bouché, Clara H, Garnier, Jean-Pierre, Choukem, Siméon-Pierre, Gautier, Jean-François
Format Journal Article
LanguageEnglish
Published England British Medical Journal Publishing Group 29.07.2015
BMJ Publishing Group LTD
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Abstract Hand washing before glucose and ketone fingerprick testing prevents false results in users of skin lightening cosmetics
AbstractList Hand washing before glucose and ketone fingerprick testing prevents false results in users of skin lightening cosmetics
Hyperglycaemia associated with ketosis reflects severe insulin deficiency that mandates immediate insulin therapy. Point-of-care devices to measure capillary glucose have become essential in diabetes management.1 Management of hyperglycaemic crisis has also been improved by the measurement of ß-hydroxybutyrate in a fingerprick blood specimen. The method is quick, accurate, and reliable,2 3 4 and recommended to medical care providers and patients.2 5 6 Here we report two cases of misleadingly high capillary glucose and ketone measurements that could have been prevented by careful hand washing. We also identify the chemical compound, hydroquinone, that interferes with capillary results.
Author Choukem, Siméon-Pierre
Garnier, Jean-Pierre
Bouché, Clara H
Gautier, Jean-François
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  givenname: Clara H
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  organization: Biochemistry Laboratory, Saint-Louis University Hospital, Assistance Publique - Hôpitaux de Paris, University Paris Descartes, 75010 Paris, France
BackLink https://www.ncbi.nlm.nih.gov/pubmed/26223684$$D View this record in MEDLINE/PubMed
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CitedBy_id crossref_primary_10_1371_journal_pone_0202271
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Snippet Hand washing before glucose and ketone fingerprick testing prevents false results in users of skin lightening cosmetics
Hyperglycaemia associated with ketosis reflects severe insulin deficiency that mandates immediate insulin therapy. Point-of-care devices to measure capillary...
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StartPage h3879
SubjectTerms 3-Hydroxybutyric Acid - analysis
3-Hydroxybutyric Acid - blood
Adult
Biomarkers - analysis
Biomarkers - blood
Blood Glucose - analysis
Blood Glucose - metabolism
Capillaries
Cosmetics
Diabetes
False Positive Reactions
Female
Glucose
Hand Disinfection
Humans
Hydroquinones - analysis
Hyperglycemia - blood
Hyperglycemia - diagnosis
Insulin
LESSON OF THE WEEK
Patients
Skin
Skin Lightening Preparations - adverse effects
Title Falsely elevated capillary glucose and ketone levels and use of skin lightening creams
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