Effect of Ca2+ deprivation on release of luteinizing hormone induced by luteinizing hormone releasing hormone from female rat pituitary glands in vitro

• Published in: Journal of endocrinology Vol. 94; no. 1; pp. 11 - 20
• Main Authors: de Koning, J, Tijssen, A. M. I, van Dieten, J. A. M. J, van Rees, G. P
• Format: Journal Article
• Language: English
• Published: England BioScientifica 01.07.1982
• Subjects: Animals; Bucladesine - analogs & derivatives; Bucladesine - pharmacology; Calcium - metabolism; Cycloheximide - pharmacology; Egtazic Acid - pharmacology; Female; Gonadotropin-Releasing Hormone - pharmacology; In Vitro Techniques; Luteinizing Hormone - metabolism; Pituitary Gland - drug effects; Pituitary Gland - metabolism; Protein Biosynthesis; Rats; Rats, Inbred Strains; Theophylline - pharmacology

Continuous exposure of hemi-pituitary glands from intact female rats to LH releasing hormone (LH-RH) in vitro displayed three phases in the pattern of LH release: during the first hour release of LH was low (first phase response), then it increased to a higher level during the second hour and remain...