Scavenger receptor B1 involvement in chronic obstructive pulmonary disease pathogenesis

• Published in: Redox experimental medicine Vol. 2023; no. 1; pp. 1 - 7
• Main Authors: Cervellati, Carlo, Casolari, Paolo, Pecorelli, Alessandra, Sticozzi, Claudia, Nucera, Francesco, Papi, Alberto, Caramori, Gaetano, Valacchi, Giuseppe
• Format: Journal Article
• Language: English
• Published: Bioscientifica Ltd 04.09.2023; Bioscientifica
• Subjects: 4-hydroxy-2-nonenal; cigarette smoking; oxidative stress; cigarette smoking; 4-hydroxy-2-nonenal; oxidative stress

Objective Chronic obstructive pulmonary disease (COPD) is one of the main causes of morbidity and mortality in the United States. Oxidative stress due to cigarette smoking seems to be one of the major driving mechanisms in COPD pathogenesis. Since the scavenger receptor B1 (SR-B1) appears to play a...