Outcome of Neoadjuvant Intra-Arterial Chemotherapy and Radical Hysterectomy for Treatment of Bulky Stage IB to Stage IIB Uterine Cervical Cancer: Can Postoperative Irradiation Be Avoided?

• Published in: International journal of gynecological cancer Vol. 26; no. 7; pp. 1258 - 1263
• Main Authors: Ujihira, Takafumi, Ota, Tsuyoshi, Kusunoki, Soshi, Sugimori, Yayoi, Kimura, Miki, Kaneda, Hiroshi, Terao, Yasuhisa, Ogishima, Daiki, Takeda, Satoru
• Format: Journal Article
• Language: English
• Published: United States Elsevier Limited 01.09.2016
• Subjects: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cancer therapies; Carcinoma, Squamous Cell - mortality; Carcinoma, Squamous Cell - therapy; Cervical cancer; Chemotherapy; Female; Humans; Hysterectomy; Infusions, Intra-Arterial; Japan - epidemiology; Lymphatic system; Medical prognosis; Middle Aged; Neoadjuvant Therapy; Prospective Studies; Radiation therapy; Treatment Outcome; Uterine Cervical Neoplasms - mortality; Uterine Cervical Neoplasms - therapy

We evaluated whether our neoadjuvant intra-arterial chemotherapy (NAIC) effectively precludes the need for postoperative radiation therapy in patients treated by radical hysterectomy for IB2 to IIB cervical cancer. Study subjects were 52 patients with a bulky cervical tumor diagnosed and treated at...