Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets - Bennett, John M; Narwal, Sunil K; Kabeche, Stephanie; Abegg, Daniel; Hackett, Fiona; Yeo, Tomas; Li, Veronica L; Muir, Ryan K; Faucher, Franco F; Lovell, Scott; Blackman, Michael J; Adibekian, Alexander; et al. (bioRxiv, 2024)
Keywords: Antiparasitic agents; Isomers; Malaria; Microbiology; Multidrug resistance; Natural products; Parasite resistance; Parasites; Phosphonates; Plasmodium falciparum; Serine; Plasmodium; serine hydrolases; activity-based probes; Activity-Based Protein Profiling; Drug Resistance; lipid metabolism; Serine Hydrolase