S41 Expression of functional receptor activity modifying protein (RAMP)-1 by airway epithelial cells with dysregulation in asthma

• Published in: Thorax Vol. 65; no. Suppl 4; p. A21
• Main Authors: Kay, A B, Bonner, K, Kariyawasam, H H, Ali, F R, Clark, P
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and British Thoracic Society 01.12.2010; BMJ Publishing Group LTD

Introduction and ObjectivesEpithelial cell expression of calcitonin-gene-related peptide (CGRP) is a feature of provoked asthma. Receptor activity modifying protein 1 (RAMP1) and the calcitonin-receptor-like receptor (CRLR) combine to form the CGRP1 receptor. We determined whether functional RAMP1 i...