AB1118 HUMAN CD141+ DENDRITIC CELLS (DCs) REPRESENT A UNIQUE TOLEROGENIC DC SUBSET THAT INDUCE IMMUNE-TOLERANCE IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS

• Published in: Annals of the rheumatic diseases Vol. 83; no. Suppl 1; pp. 1890 - 1891
• Main Authors: Yuan, X., Sun, L., Qin, X., Wang, Y., Chen, Y., Liu, S., Wang, D.
• Format: Journal Article
• Language: English
• Published: Kidlington BMJ Publishing Group Ltd and European League Against Rheumatism 01.06.2024; Elsevier B.V; Elsevier Limited
• Subjects: Autoimmune diseases; CD11c antigen; CD163 antigen; CD1c antigen; CD3 antigen; CD40 antigen; CD80 antigen; CD83 antigen; CD86 antigen; Cell differentiation; Cell migration; Cell therapy; Cytokines and Chemokines; Dendritic cells; Flow cytometry; FLT3L protein; Homeostasis; Immunological tolerance; Immunoregulation; Innate immunity; Interleukin 10; Lupus; Lymphocytes T; Mesenchymal stem cells; Peripheral blood; Pluripotency; Scientific Abstracts; Stem cell transplantation; Stem cells; Systemic lupus erythematosus; Innate immunity; Cytokines and Chemokines

Background:Tolerogenic dendritic cells (DCs) offer promising prospects as cell-based treatment for autoimmune diseases, including systemic lupus erythematosus (SLE). However, the precise mechanisms accounting for tolerogenic DCs mediated immunoregulation in SLE remain incompletely understood.Objecti...