AB1161 DECREASED ADAMTS13 ACTIVITY IN SCLERODERMA RENAL CRISIS

• Published in: Annals of the rheumatic diseases Vol. 83; no. Suppl 1; p. 1914
• Main Authors: Tsuji, H., Shirakashi, M., Hiwa, R., Kitagori, K., Akizuki, S., Nakashima, R., Onishi, A., Yoshifuji, H., Tanaka, M., Morinobu, A.
• Format: Journal Article
• Language: English
• Published: Kidlington BMJ Publishing Group Ltd and European League Against Rheumatism 01.06.2024; Elsevier B.V; Elsevier Limited
• Subjects: Anemia; Angiotensin-converting enzyme inhibitors; Autoantibodies; Biomarkers; Blood pressure; Diagnostic test; Hemodialysis; Hemoglobin; Hemolytic anemia; Hypertension; Kidneys; Medical prognosis; Metalloproteinase; Morbidity; Prognosis; Prognostic factors; Purpura; Renal function; Rheumatology; Scientific Abstracts; Scleroderma; Survival; Systemic sclerosis; Thrombocytopenia; Thrombocytopenic purpura; Thrombospondin; Thrombotic microangiopathy; Thrombotic thrombocytopenic purpura; Biomarkers; Diagnostic test; Autoantibodies; Kidneys; Prognostic factors

Background:Thrombotic microangiopathy (TMA) is associated with the progression of scleroderma renal crisis (SRC). TMA may be involved in normotensive renal crisis, which has a poor prognosis. A disintegrin-like and metalloprotease with thrombospondin type 1 repeats (ADAMTS)-13 is useful for the diag...