Protein Kinase A-Independent cAMP Stimulation of Progesterone in a Luteal Cell Model Is Tyrosine Kinase Dependent but Phosphatidylinositol-3-Kinase and Mitogen-Activated Protein Kinase Independent1

• Published in: Biology of reproduction Vol. 77; no. 1; pp. 147 - 155
• Main Authors: Needle, Elie, Piparo, Kathy, Cole, Donna, Worrall, Carolyn, Whitehead, Ian, Mahon, Gwen, Goldsmith, Laura T
• Format: Journal Article
• Language: English
• Published: Society for the Study of Reproduction, Inc 01.07.2007
• Subjects: corpus luteum; corpus luteum function; female reproductive tract; progesterone; signal transduction

Comprehensive understanding of the cellular mechanisms utilized by luteal cells in response to extracellular hormonal signals resulting in the normal synthesis and secretion of their steroid and peptide products has yet to be achieved. Previous studies have established that cAMP functions as a secon...